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Breakthrough Therapies for Autoimmune Diseases & Cancer

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Precision Targeting of Highly Cytotoxic T Cells in Autoimmune Disease

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Abcuro Announces Topline Results from the MUSCLE Study of Ulviprubart in Patients with Inclusion Body Myositis

February 24, 2026

Phase 2/3 study did not meet primary or key secondary endpoints; ulviprubart showed a favorable safety and tolerability profile compared to placebo Clinically meaningful slowing of disease progression observed in patients with mild to moderate disease; establishes basis for advancing ulviprubart in this segment of the population  Study results to be presented at the 6th

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February 24, 2026
Abcuro Announces Topline Results from the MUSCLE Study of Ulviprubart in Patients with Inclusion Body MyositisPress Releases

Targeting Highly Cytotoxic T Cells

Highly cytotoxic T cells have been implicated as mediators of tissue damage in many autoimmune diseases

 

Ulviprubart in Autoimmune Disorders

Ulviprubart, an investigational monoclonal antibody, selectively depletes highly cytotoxic T cells

 

Inclusion Body Myositis

Inclusion body myositis (IBM) is a debilitating chronic, progressive disorder in which muscle is destroyed by highly cytotoxic T cells

 

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